题目：Metabolic regulation by nuclear receptor FXR and miRNA-34a in healthy and obese state

报告人：付婷 博士

时 间：2015年1月7日（星期三）上午10:00

地 点：生物楼一楼中厅

付婷博士主要发表文章有：
1. Sunmi Seok*, Ting Fu*, Sung-E Choi, Yang Li, Rong Zhu, Subodh Kumar, Xiaoxiao Sun, Gyesoon Yoon, Yup Kang, Wenxuan Zhong, Jian Ma, Byron Kemper, and Jongsook Kim Kemper. Transcriptional regulation of autophagy by an FXR/CREB1 axis (*equal contribution to this work) Nature, 516, 108–111 (04 December 2014) doi:10.1038/nature13949
Highlighted in a review article, Cell metabolism: Autophagy transcribed, C. Settembre & A. Ballabio, Nature, doi:10.1038/nature13939.
Highlighted in a review article, Nutrient-sensing and autophagic genes in fed and fasted states, Nature Reviews Endocrinology (2014) doi:10.1038/nrendo.2014.212
2. Ting Fu, Sunmi Seok, Sung-E Choi, Zhang Huang, Kelly Suino-Powell, H. Eric Xu, Byron Kemper, and Jongsook Kim Kemper. MiR-34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte FGF21 signaling and SIRT1 function. Molecular and Cellular Biology, selected as a Spotlight paper, 2014 Nov 15; 34(22):4130-42.
3. Ting Fu, SungE Choi, Dong-Hyun Kim, Sunmi Seok, Kelly Suino-Powell, H. Eric Xu, and Jongsook Kim Kemper. Aberrantly elevated miR-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho. PNAS,2012 Oct 2;109(40):16137-42