报告题目：水稻谷蛋白合成运输和积累的分子机理研究
报告人：万建民教授、南京农业大学
时间：2015年3月22日（周日）下午15:00
地点：金沙8888js官方一楼中厅
万建民，教授，博士生导师，水稻分子遗传与育种专家。1982年获南京农业大学农学专业学士学位，1985年获南京农业大学作物遗传育种硕士学位，1995年获日本京都大学农学博士学位。1996年任日本京都大学农学部特别研究员，1997.1-2001.1年任日本农林水产省农业研究中心研究员。2000年回国，任南京农业大学农学院教授、博士生导师、农学院院长。2003年7月至今，担任中国农业科学院作物科学研究所所长。2004年起，兼任中国作物学会常务副理事长、中国农业生物技术学会副理事长、国家转基因生物新品种培育科技重大专项技术总师、国家发改委生物技术产业咨询委员会副秘书长、国家“863”计划“作物分子育种”项目负责人。
万建民长期从事水稻优异基因挖掘和分子育种研究，在国内较早提出和初步实践了作物分子设计育种。先后主持国家863计划、国家自然科学基金、农业部超级稻专项和国际合作项目等多项重大课题，组织和协调全国南方粳稻的分子育种工作。带领团队建立了相关研究体系，在水稻籼粳交杂种优势利用基础研究（包括杂种不育、超亲晚熟、株高超亲）、品质优异基因挖掘（外观品质垩白和粒型、食味品质淀粉和蛋白、以及功能性品质等）、抗病虫新基因挖掘（褐飞虱、灰飞虱、条纹叶枯病、黑条矮缩病）和优质高产多抗粳稻新品种选育等方面取得了重要进展，在国内较早提出和实践作物分子设计育种，构建了水稻分子育种技术体系。已图位克隆水稻重要新基因25个，培育新品种8个，其中宁粳1号、宁粳3号、宁粳4号三个品种被农业部确认为超级稻品种，得到大面积的推广应用。获得新品种权15项、发明专利20项。在Nature、Nature Communications、Developmental Cell、PNAS、Plant Cell、PLOS Genetics、Plant J.、Plant Physiology等SCI刊物发表论文150余篇，出版专著3部。培养的博士生有3人获全国优秀博士学位论文提名奖。
研究成果“抗条纹叶枯病高产优质粳稻新品种选育及应用” 2010年获国家科技进步一等奖（第一完成人），另外，获省部级一等奖3项，二等奖3项。被授予全国优秀农业科技工作者、农业部及江苏省有突出贡献中青年专家和江苏省“五一”劳动奖章等荣誉称号。2006年入选新世纪百千万人才工程国家级人选，2012年入选国家万人计划和科技部创新团队，2012年获得何梁何利基金科学与技术进步奖。2013年，万建民教授课题组科研人员在控制水稻分蘖的新激素信号转导研究中取得了开创性进展，12月11日在线出版的国际顶级杂志——《自然》以Article Research形式刊登了相关研究成果。
近期代表性论文
1. Zhou Feng, Lin Qibing, Zhu Lihong, Ren yulong, Zhou Kunneng, Shabek Nitzan, Wu Fuqing, Dong Wei, Gan Lu, Gao He, Wang Dan, Tan Junjie, Ma Weiwei, Zhang Xin, Guo Xiuping, Wang JiuLin, Chen Weiqi, Chu Jinfang, Yan Cunyu, Cheng Zhijun, Wang Jie, Lei Cailin, Zhai Huqu, Wu Chuanyin, Wang Haiyang, Jiang Ling, Liu Xi, Zheng Ning.Wan JM. D14–SCFD3-dependent degradation of D53 regulates strigolactone signalling. Nature 2013, 504: 406-410
2. Zhigang Zhao, Yunhui Zhang, Xi Liu, Xin Zhang, Shichang Liu, Xiaowen Yu, Yulong Ren,
Xiaomin Zheng, Kunneng Zhou, Ling Jiang, Xiuping Guo, Ying Gai, Chuanyin Wu, Huqu Zhai,
Haiyang Wang, Jianmin Wan. A role for a dioxygenase in auxin metabolism and reproductive development in rice. Developmental Cell, 2013, 27(1):113-122
3. Qibing Lin, Dan Wang, Hui Dong, Suhai Gu, Zhijun Cheng, Jie Gong, Ruizhen Qin, Ling Jiang, Gang Li, Jiu Lin Wang, Fuqing Wu, Xiuping Guo, Xin Zhang, Cailin Lei, Haiyang Wang, Jianmin Wan. Rice APC/CTE controls tillering by mediating the degradation of MONOCULM1. Nature Comminucation, 2012.3.20 DOI: 10.1038/ncomms1716
4. Wu WX, Zheng XM, Lu GW, Zhong ZZ. Gao H, Chen LP, Wu CY, Wang HJ, Wang Q, Zhou KN, Wang JL, Wu FQ, Zhang X, Guo XP, Cheng ZJ, Lei CL, Lin QB, Jiang L, Wang HY, Ge S, Wan JM. Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia. Proc Natl Acad Sci U S A,2013, 110 (8): 2775-2780
5. Yulong Ren, Yihua Wang, Feng Liu, Kunneng Zhou, Feng Zhou, Kai Liu, Ying Wang, Xiaohua Han, Xin Zhang, Xiuping Guo, Fuqing Wu, Zhijun Cheng, Jiulin Wang, Cailin Lei, Qibing Lin, Ling Jiang, Chuanyin Wu, Yiqun Bao, Haiyang Wang, Jianmin Wan. GLUTELIN PRECURSOR ACCUMULATION3 Encodes a Regulator of Post-Golgi Vesicular Traffic Essential for Vacuolar Protein Sorting in Rice Endosperm. The Plant Cell. 2014,26: 410–425
6. Liguo Zhang, Zhijun Cheng, Ruizhen Qin, Yang Qiu, Jiulin Wang, Dan Wang, Xin Zhang, Xiuping Guo, Ling Jiang, Chuanyin Wu, Haiyang Wang, Xiaofeng Cao, Jianmin Wan. Identification and Characterization of an Epi-allele of OsFIE1 Reveals a Regulatory Linkage between two Epigenetic Marks in Rice. The Plant Cell, 2012, 24: 4407-4421
7. Shirong Zhou;Yang Wang; Wanchang Li; Zhigang Zhao; Yong Wang; Suhai Gu ; Qibing Lin ; Dan Wang; Ling Jiang; Ning Su; Xin Zhang; Linglong Liu; Zhijun Cheng; Cailin Lei ;Jiulin Wang; Xiuping Guo; Fuqing Wu; Haiyang Wang; Hiroshi Ikehashi, Jianmin Wan. Pollen Semi-Sterility1 Encodes a Kinesin-1 like protein required for male meiosis, anther dehiscence and fertility in rice. The Plant Cell, 2011, 23: 111-129
8. Wu CY, Trieu A, Radhakrishnan P, Kwok SF, Harris S, Zhang K, Wang JL, Wan JM, Zhai HQ, Takatsuto S, Matsumoto S, Fujioka S, Feldmann KA, Pennella RI. Brassinosteroids regulate grain filling in rice. The Plant Cell, 2008, 20: 2130–2145
9. He Gao, Xiao-Ming Zheng, Guilin Fei, Jun Chen, Mingna Jin, Yulong Ren, Weixun Wu, Feng
Zhou, Jie Wang, Xin Zhang, Xiuping Guo, Jiu-Lin Wang, Zhijun Cheng, Chuanyin Wu, Haiyang Wang, Jian-Min Wan. Ehd4, a CCCH-type positive regulator of photoperiodic flowering in rice. Plos Genetics, 2013, 9(2): e1003281, www.plosgenetics.org
10. Ma XF, Cheng ZJ, Qin RZ, Qiu Y, Heng YQ, Yang H, Ren YL, Wang XL, Bi JC, Ma XD, Zhang
X, Wang JL, Lei CL, Guo XP, Wang J, Wu FQ, Jiang L, Wang HY, Wan JM. OsARG encodes an
arginase that plays critical roles in panicle development and grain production in rice. The Plant Journal. 2013, 73(2):190-200
11. Yihua Wang, Yulong Ren, Xi Liu, Ling Jiang, Liangming Chen, Xiaohua Han, Mingna Jin, Shijia Liu, Feng Liu, Jia Lv, Kunneng Zhou, Ning Su, Yiqun Bao, Jianmin Wan. OsRab5a regulates endomembrane organization and storage protein trafficking in rice endosperm
cells. The Plant Journal ,2010, 64, 812–824
12. Wang YH, Zhu SS, Liu SJ, Jiang L, Chen LM, Ren YL, Han XH, Liu F, Ji SL, Liu X, Wan JM. The vacuolar processing enzyme OsVPE1 is required for efficient glutelin processing in rice. The Plant Journal, 2009, 58: 606–617
13. Dong H, Fei GL, Wu CY, Wu FQ, Sun YY, Chen MJ, Ren YL, Zhou KN, Cheng ZJ, Wang JL,
Jiang L, Zhang X, Guo XP, Lei CL, Su N, Wang HY, Wan JM. A rice Virescent-Yellow leaf mutant reveals new insights into the role and assembly of plastid caseinolytic protease in higher plants. Plant Physiology, 2013, 162: 1867–1880
14. Ning Su, Mao-Long Hu, Dian-Xing Wu, Fu-Qing Wu, Gui-Lin Fei, Ying Lan, Xiu-Ling Chen,
Xiao-Li Shu, Xin Zhang, Xiu-Ping Guo, Zhi-Jun Cheng, Cai-Lin Lei, Cun-Kou Qi, Ling Jiang, Hai-Yang Wang, Jian-Min Wan. Disruption of a rice Pentatricopeptide Repeat protein causes
a seedling-specific albino phenotype and its utilization to enhance seed purity in hybrid rice production, Plant Physiology 2012, 159: 227–238
15. Wei XJ, Xu JF, Guo HN, Jiang L, Chen SH, Yu CY, Zhou ZL, Hu PS, Zhai H, Wan JM. DTH8
suppresses flowering in rice, influencing plant height and yield potential simultaneously, Plant Physiology, 2010, 153: 1747–1758
16. Wu ZM, Zhang X, He B, Diao LP, Sheng SL, Wang JL, Guo XP, Su N, Wang LF, Jiang L, Wang CM, Zhai HQ, Wan JM*. A chlorophyll-deficient rice mutant with impaired chlorophyllide esterification in chlorophyll biosynthesis. Plant Physiology, 2007, 145: 29-40
17. Feng Liu, Yulong Ren, Yihua Wang, Cheng Peng, Kunneng Zhou, Jia Lv, Xiuping Guo, Xin
Zhang, Mingsheng Zhong, Shaolu Zhao, Ling Jiang, Haiyang Wang, Yiqun Bao, Jianmin Wan. OsVPS9A functions cooperatively with OsRAB5A to regulate post-Golgi dense vesicle-
mediated storage protein trafficking to the protein storage vacuole in rice endosperm cells. Molecular Plant, 2013, 6 (6): 1918-1932
18. Hui Li, Ling Jiang, Ji-Hyun Youn, Wei Sun, Zhijun Cheng, Tianyun Jin, Xiaoding Ma, Xiuping Guo, Jiulin Wang, Xin Zhang, Fuqing Wu, Chuanyin Wu, Seong-Ki Kim, Jianmin Wan. A comprehensive genetic study reveals a crucial role of CYP90D2/D2 in regulating plant architecture in rice (Oryza sativa). New Phytologist, 2013, 200: 1076-1088
19. Han Xiaohua, Wang Yihua, Liu Xi, Jiang Ling, Ren Yulong, Liu Feng, Peng Cheng, Li Jingjing, Jin Ximing, Wu Fuqing, Wang Jiulin, Guo Xiuping, Zhang Xin, Cheng Zhijun, Wan Jianmin. The failure to express a protein disulphide isomerase like protein results in a floury endosperm and an endoplasmic reticulum stress response in rice. J Exp Bot, 2012, 63(1): 121-130
20. Weng JF, Gu SH, Wan XY, Gao H, Guo T, Su N, Lei CL, Zhang X, Cheng ZJ, Guo XP, Wang JL, Jiang L, Zhai HQ, Wan JM. Isolation and initial characterization of GW5, a major QTL associated with rice grain width and weight. Cell Research 2008, 18: 1199-1209.
