NIH-funded postdoctoral positions in cancer biology are available inDr. Shi-Yuan Cheng’slaboratory, a highly productive and dynamic research team with an established track record of basic and translational research and mentoring future faculty (http://labs.feinberg.northwestern.edu/cheng/),at Lou & Jean Malnalti Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Simpson Querrey Institute for Epigenetics at Northwestern University Feinberg School of Medicine in Chicago, IL, USA.

The Cheng Laboratory investigates mechanisms that regulate phenotypes and therapy responses of cancer using patient-derived cancer stem cells (GSCs), PDX, human induced pluripotent stem cell (hiPSC)-derived cancer spheroids, clinical specimens, orthotopic tumor xenografts, and other model systems, and state-of-art techniques of biochemical, molecular, cellular, and bioinformatics. NIH T32 training award opportunities are possible at the Lurie Cancer Center for candidates who are US citizen or permanent resident. We are seeking ambitious and outstanding postdocs who are interested in studying the following research areas:

1) Non-coding RNAs (circular RNAs and long non-coding RNAs) in cancer.

2)Multi-omics with emphasis of proteomics and cancer non-response to immunotherapy.

3)Mechanisms of cancer therapy-resistance and targeting development.

4) Other projects in cancer that can be initiated by self-driven, capable, and independent postdocs.

The applicants should have a PhD degree in biochemistry, molecular biology, cancer biology, and well-trained with proficient skills in studying cellular signaling, RNA biology, biochemistry, gene regulation with desired bioinformatic experience.The applicants must have strong publication records with first-author papers in high-impact journals.Fellows areexpected to be independent,highly motivated with strong drive to succeed,capable of leading their own research projects and be in charge of all aspects of their project from conception, data generation and analysis to grant submissions and preparation of scientific publications under the guidance of the PI,believe in team science and collaborative, and proficient in English communications.

Selected publications from Cheng Laboratory:Mol Cell,(2021),Nat Cell Biol.,(2021),Cancer Cell(2017),Autophagy(2019);Nature Comm.,(2016),J. Clin. Invest.(2011, 2014); Proc. Natl. Acad. Sci., USA, (2013).

Please submit a letter of interest, your resume, reprints of relevant publications, and contact information of three references including the PhD mentor.Northwestern University provides NIH-standard annual salaryfor postdoctoral fellows (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-21-049.htmland an excellent compensation and benefits packagehttps://www.northwestern.edu/hr/benefits/postdoc-benefits.html.

Northwestern University is an Equal Opportunity/Affirmative Action Educator and Employer and invites applications from all qualified individuals. Applications from women and minorities are especially sought.

Contact:

Shi-Yuan Cheng, PhD

Professor, Zell Scholar & AAAS Fellow

The Ken and Ruth DaveeDepartment of Neurology

Lou & Jean Malnati Brain Tumor Institute of Northwestern Medicine

Simpson Querrey Institute for Epigenetics

The Robert H. Lurie Comprehensive Cancer Center

Northwestern University Feinberg School of Medicine

303 E. Superior, Lurie 6-119

Chicago, IL 60611, USA

Office: 1-(312)503-3043

E-mail: shiyuan.cheng@northwestern.edu, shiyuancheng@gmail.com

Lab website:http://labs.feinberg.northwestern.edu/cheng/

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