他的朋友在MD Anderson 做PI，想招博士后，
A postdoctoral fellow position is available in Department of Immunology. Our research is to understand the molecular basis of T cell mediated immune responses, and how abnormal immune regulation leads to immunodeficiency, autoimmunity and cancer. Autoimmunity and inflammation mouse models include experimental autoimmune encephalomyelitis (EAE), colitis, and lung airway inflammation; tumor immunity models include T cell-mediated immune responses against transplanted melanoma, chemical induced sarcoma, and lung cancer. A postdoctoral fellow would be involved in the research in the following projects: 1. The molecular mechanisms of T cell activation and tolerance; 2. The signaling and transcriptional mechanisms underlying T helper cell differentiation and function.
Candidates should have a recent Ph.D. degree or in the process of completing Ph.D. training and a solid background in Immunology, with preferred hand-on experience in flow cytometry, molecular techniques, and mouse models of autoimmunity and/or anti-tumor immunity.
Send curriculum vitae and names of three references to: Dr. Roza Nurieva, Department of Immunology, E-mail:rnurieva@mdanderson.org.
PRESENT TITLE AND AFFILIATION
Associate Professor, Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX
Member, Graduate Faculty, The University of Texas Graduate School of Biomedical Sciences (GSBS), Houston, TX
The University of Texas MD Anderson Cancer Center
Degree-Granting Education
Kazan State University, Kazan, Russia, Russian Federation, BS, 1994, Biochemistry
Pushchino State University, Pushchino, Russia, Russian Federation, MS, 1996, Biology
Pushchino State University, Moscow, Russian Federation, PHD, 1999, Immunology & Biochemistry
Postdoctoral Fellowship, Immunology, University of Washington, Seattle, WA, 1/2001-12/2004
Research Scientist, Branch of S & O, Group of Regulatory Proteins, Institute of Bioorganic Chemistry, Pushchino, Russia, Russian Federation, 12/1999-5/2000
Senior Fellow, Department of Immunology, University of Washington, Seattle, WA, 1/2001-12/2004
Instructor, Department of Immunology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX, 1/2005-7/2008
Assistant Professor, Non-Tenure Track, Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, 8/2008-8/2011
Assistant Professor, Department of Immunology, Tenure-Track, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2011-8/2017
Member, Graduate Faculty, The University of Texas Graduate School of Biomedical Sciences (GSBS), Houston, TX, 2017-present
Associate Professor, Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2017-present
International Soros Science Education Program, 1989-2000
Arthritis Foundation Postdoctoral Fellowship, Arthritis Foundation, 2003-2006
Federation of Clinical Immunology Societies Centers of Excellence Trainee Satellite Symposium Travel Grant, 2004
Arthritis Foundation Travel Award, Arthritis Foundation, 2005
Scientist Development Grant, American Heart Association (AHA), 2006-2009
Arthritis Foundation Travel Award, Arthritis Foundation, 2007
BioSymposia Young Investigator Travel Award, 2008
Junior Faculty Travel Grant, American Association of Immunologists (AAI), 2009-2012
Pfizer-Showell Travel Award, American Association of Immunologists (AAI)/Henry J. Showell and Pfizer, Inc., 2010
Travel Award Grant, 14th International Congress of Immunology, American Associations of Immunologists (AAI), 2010
Top 1% of Highly Cited Researchers, Thomson Reuters, 2014
American Association of Immunologists (AAI) Travel Award Grant for the 4th European Congress of Immunology, American Association of Immunologists (AAI), 2015
Junior Faculty Travel Grant, American Association of Immunologists (AAI), 2015-2017
The Journal of Biological Chemistry/Herbert Tabor Young Investigator Award, International Cytokine and Interferon Society (ICIS), 2015
Principal Investigator, Start-Up Funds, The University of Texas MD Anderson Cancer Center, 9/1/2011-8/31/2019, $750,000
Principal Investigator, Grail deficiency promotes intestinal inflammation and cancer development, The University of Texas MD Anderson Cancer Center - Center for Inflammation and Cancer (CIC), 12/1/2013-11/30/2019, $30,000 ($30,000/year)
Principal Investigator, Role of T follicular helper cells in anti-tumor immunity, 2015-13015459-Y1, The University of Texas MD Anderson Cancer Center - Center for Inflammation and Cancer (CIC), 7/7/2015-present, $30,000 ($30,000/year)
Principal Investigator, 0.12 months, Enhancing anticancer T cell reactivity by targeting grail, 2016-00051130-Y2, The University of Texas MD Anderson Cancer Center - Bridge Funding, 12/1/2015-6/30/2018, $74,954 ($74,954/year)
Principal Investigator, 1.8 months, STAT1: New regulator of inflammatory Th17 and Th2 cells, 5R21AI20012-02, NIH/NIAID, 1/15/2016-12/31/2018, $275,000 ($125,000/year)
Principal Investigator, 1.8 months, Therapeutic potential of follicular helper T cells for melanoma treatment, 2016-00053042-Y1, The University of Texas MD Anderson Cancer Center - Institutional Research Grant (IRG), 9/1/2016-1/31/2019, $75,000 ($37,500/year)
Principal Investigator, 3.6 months, Role of Cul4A in Th2 tolerance and airway inflammation, 1R56AI125269-01A1, NIH/NIAID, 3/13/2017-2/28/2019, $187,500 ($187,500/year)
Principal Investigator, 0.6 months, Grail-targeting breaks the immune tolerance to melanoma, 5R03CA219760-02, NIH/NCI, 7/1/2017-6/3/2019, $100,000 ($50,000/year)
Principal Investigator-MDACC, 1.2 months, B cell anergy, acLDL uptake and altherosclerosis, 1R01HL139000-01A1, NIH/NIAID, 4/1/2018-3/31/2022, $333,447 ($65,135/year)
Co-Investigator, 0.12 months, Isoform-specific targeting of the PI3Ks to overcome cancer immunoresistance, Melanoma Research Alliance/MD Anderson Partnership, PI - Peng, 6/1/2018-5/31/2021, $225,000 ($75,000/year)
Principal Investigator, Careers in Immunology Fellowship - Role of T Follicular Helper Cells in Anti-Tumor Immunity, American Association of Immunologists (AAI), 9/1/2018-8/31/2019, $48,804 ($48,804/year)
Principal Investigator, 2.4 months, Role of Cul4A in governing Th2-type tolerance, 1R01HL143520-01, NIH/NHLBI, 9/1/2018-6/30/2023, $1,250,000 ($250,000/year)
Principal Investigator, 3.6 months, Role of E3 Ubiquitin Ligase RNF133 in T Cell Function and Tolerance, 1R01HL141966-01A1, NIH/NHLBI, 9/1/2018-8/31/2023, $1,250,000 ($250,000/year)
Principal Investigator, 0.6 months, Function of T Follicular Helper Cells in Anti-Tumor Immunity, 1R03CA235009-01, NIH/NCI, 12/1/2018-11/30/2020, $100,000 ($50,000/year)
Co-Investigator, 1.2 months, T Follicular Helper Cells in the Pathogenesis of Chronic Lymphocytic Leukemia, RP190386, Cancer Prevention & Research Institute of Texas (CPRIT), PI - Ma, 3/1/2019-2/28/2022, $1,140,000 ($380,000/year)
Principal Investigator, 2.4 months, Therapeutic Potential of T Follicular Helper Cells for Melanoma Treatment, RP180513, Cancer Prevention & Research Institute of Texas (CPRIT), 3/1/2019-2/28/2022, $859,038 ($285,002/year)
Co-Investigator, 0.6 months, Preventing Autoreactive T Cell Mediated Inflammatory Demyelinating Disease Using a Small Molecule Integrin Agonist, 1R21AI137729-01A1, NIH/NIAID, PI - Hailemichael, 4/1/2019-3/31/2021, $250,000 ($125,000/year)
Principal Investigator, 2.4 months, Ubiquitination in B Cell Tolerance and Autoimmunity, 1R01AI144202-01, NIH/NIAID, 4/1/2019-3/31/2024, $1,250,000 ($250,000/year)
Principal Investigator, 3.6 months, ICOS-B7h interaction in humoral immunity and rheumatoid arthritis, Arthritis Foundation, 10/1/2003-9/30/2006, $105,000 ($35,000/year)
Principal Investigator, 3.6 months, The role of ICOS-B7h in atherosclerosis, American Heart Association, 1/1/2006-12/31/2009, $260,000 ($65,000/year)
Principal Investigator, 3.6 months, Regulation of T cell activation and tolerance by grail, 1 R01 AI083761-04, NIH/NIAID, 6/1/2009-5/31/2014, $1,250,000 ($250,000/year)
Co-Principal Investigator, 3.6 months, Transcriptome and epigenome analysis of helper T cell specification and plasticity, 1RC2AR59010-01, NIH/NIAMS, PI - Chen Dong, PhD, 9/30/2009-9/29/2011, $280,000 ($140,000/year)
Co-Investigator, 0.6 months, The role of complement system in alloimmune responses, 1R21AI101932, NIH/NCI, PI - Qing Ma, 8/1/2012-7/31/2014, $275,000 ($137,500/year)
Co-Investigator, 0.6 months, Effector and memory T follicular helper cells, 5R01AI106654-02, NIH/NIAID, PI - Dong, 7/1/2013-6/30/2016, $157,048 ($52,349/year)
Principal Investigator, 1.2 months, Regulation of T cell activation and function by Cul4A, The University of Texas MD Anderson Cancer Center - Institutional Research Grant (IRG), 2/1/2014-1/31/2016, $25,000 ($25,000/year)
Principal Investigator, 1.2 months, Role of Grail in maintaining humoral immune tolerance, 5R03AI120027-02, NIH/NIAID, 6/15/2015-5/31/2018, $100,000 ($50,000/year)
Principal Investigator, 0.6 months, Melanoma SPORE Career Development Award (CDA) - The role of regulation of follicular T cells in tumor immunity, The University of Texas MD Anderson Cancer Center, 9/1/2016-8/31/2017, $25,000 ($25,000/year)
Principal Investigator, 1.2 months, The role and regulation of follicular helper T cells in tumor immunity, 2016-00053060-Y1, The University of Texas MD Anderson Cancer Center - Melanoma SPORE Career Development (CDA), 9/1/2016-8/31/2017, $25,000 ($25,000/year)
Peer-Reviewed Original Research Articles
1. Abdrasilov BS, Kim YuA , Nurieva RI, Dedkova EN, Leonteva GA, Park HJ, Zinchenko VP. The effect of total saponins from Panax Ginseng C.A. Meyer on the intracellular signalling system in Ehrlich ascites tumor cells. Biochem Mol Biol Int 38(3):519-26, 3/1996. PMID: 8829611.
2. Kostanyan IA, Navolotskaya EV, Nurieva RI. Identification of Binding Sites for L-Glutamate on T Lymphocytes. Russ J Immunol 2(2):135-137, 7/1997. PMID: 12687068.
3. Kostanyan IA, Merkulova MI, Navolotskaya EV, Nurieva RI. Study of interaction between L-glutamate and human blood lymphocytes. Immunol Lett 58(3):177-80, 8/1997. PMID: 9293400.
4. Kostanyan IA, Navolotskaya EV, Nurieva RI, Zav'ialov VP, Lipkin VM. [Interaction of L-glutamic acid with human T-lymphocytes]. Bioorg Khim 23(10):805-8, 10/1997. PMID: 9490616.
5. Kostanian IA, Nurieva RI, Novolotskaia EV, Astapova MV, Dranitsyna SM, Zav'ialov VP, Lipkin VM. [Effect of L-glutamic acid on the reception of cytokines by HL-60 cells]. Bioorg Khim 24(1):3-9, 1/1998. PMID: 9551194.
6. Kostanian IA, Nurieva RI, Navolotskaia EV, Astapova MV, Dranitsyna SM, Zav'ialov VP, Lipkin VM. [Mechanism of differentiating action of L-glutamic acid on HL-60 cells]. Mol Biol (Mosk) 32(1):148-53, Jan-Feb, 1/1998. PMID: 9566262.
7. Kostanyan IA, Nurieva RI, Navolotskaya EV, Astapova MV, Dranitsina SM, Bogachuk AP, Zav'yalov VP, Lipkin VM. Influence of L-glutamic acid on binding of interleukin-1beta, tumour necrosis factor-alpha and interleukin-6 to HL-60 cells. Immunol Lett 62(1):9-13, 5/1998. PMID: 9672141.
8. Kostanian IA, Nurieva RI, Lepikhova TN, Astapova MV, Navolotskaia EV, Zavialov VP, Lipkin VM. [Appearance of glutamate receptors on the surface of HL-60 cells upon differentiation]. Bioorg Khim 24(6):468-70, 6/1998. PMID: 9702357.
9. Nurieva RI, Navolotskaya EV, Lepikhova TN, Kostanyan IA, Lipkin VM. A Study of L-Glutamate Binding on Murine Peritoneal Macrophages and Its Influence on the Activity of These Cells. Russ J Immunol 3(3-4):270-273, 12/1998. PMID: 12687106.
10. Navolotskaya EV, Zargarova TA, Lepikhova TN, Turobov VI, Nurieva RI, Malkova NV, Lipkin VM, Zav'yalov VP. Study of immunosuppressive activity of a synthetic decapeptide corresponding to an ACTH-like sequence of human immunoglobulin G1. Biochemistry (Mosc) 64(7):758-64, 7/1999. PMID: 10424898.
11. Lepikhova TN, Navolotskaya EV, Zargarova TA, Nurieva RI, Lipkin VM, Zav'yalov VP. Influence of synthetic peptide corresponding to the ACTH-like sequence of human immunoglobulin G1 on proliferation of lymphoblastoid cells. Peptides 21(3):353-7, 3/2000. PMID: 10793216.
12. Nurieva RI, Duong J, Kishikawa H, Dianzani U, Rojo JM, Ho Ic, Flavell RA, Dong C. Transcriptional regulation of th2 differentiation by inducible costimulator. Immunity 18(6):801-11, 6/2003. PMID: 12818161.
13. Nurieva RI, Mai XM, Forbush K, Bevan MJ, Dong C. B7h is required for T cell activation, differentiation, and effector function. Proc Natl Acad Sci U S A 100(24):14163-8, 11/2003. e-Pub 11/2003. PMCID: PMC283563.
14. Dong C, Nurieva RI. Regulation of immune and autoimmune responses by ICOS. J Autoimmun 21(3):255-60, 11/2003. PMID: 14599850.
15. Dong C, Nurieva RI, Prasad DV. Immune regulation by novel costimulatory molecules. Immunol Res 28(1):39-48, 2003. PMID: 12947223.
16. Nurieva RI. Regulation of immune and autoimmune responses by ICOS-B7h interaction. Clin Immunol 115(1):19-25, 4/2005. PMID: 15870016.
17. Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6(11):1133-41, 11/2005. e-Pub 10/2005. PMCID: PMC1618871.
18. Yu XZ, Liang Y, Nurieva RI, Guo F, Anasetti C, Dong C. Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. J Immunol 176(12):7394-401, 6/2006. PMID: 16751384.
19. Nurieva R, Thomas S, Nguyen T, Martin-Orozco N, Wang Y, Kaja MK, Yu XZ, Dong C. T-cell tolerance or function is determined by combinatorial costimulatory signals. EMBO J 25(11):2623-33, 6/2006. e-Pub 5/2006. PMCID: PMC1478197.
20. Yang XO, Panopoulos AD, Nurieva R, Chang SH, Wang D, Watowich SS, Dong C. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J Biol Chem 282(13):9358-63, 3/2007. e-Pub 2/2007. PMID: 17277312.
21. Nurieva RI, Chuvpilo S, Wieder ED, Elkon KB, Locksley R, Serfling E, Dong C. A costimulation-initiated signaling pathway regulates NFATc1 transcription in T lymphocytes. J Immunol 179(2):1096-103, 7/2007. PMID: 17617602.
22. Nurieva R, Yang XO, Martinez G, Zhang Y, Panopoulos AD, Ma L, Schluns K, Tian Q, Watowich SS, Jetten AM, Dong C. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 448(7152):480-3, 7/2007. e-Pub 6/2007. PMID: 17581589.
23. Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 28(1):29-39, 1/2008. e-Pub 12/2007. PMCID: PMC2587175.
24. Chung Y, Nurieva R, Esashi E, Wang YH, Zhou D, Gapin L, Dong C. A critical role of costimulation during intrathymic development of invariant NK T cells. J Immunol 180(4):2276-83, 2/2008. PMID: 18250436.
25. Yang XO, Chang SH, Park H, Nurieva R, Shah B, Acero L, Wang YH, Schluns KS, Broaddus RR, Zhu Z, Dong C. Regulation of inflammatory responses by IL-17F. J Exp Med 205(5):1063-75, 5/2008. e-Pub 4/2008. PMCID: PMC2373839.
26. Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, Ma L, Wang YH, Watowich SS, Jetten AM, Tian Q, Dong C. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity 29(1):138-49, 7/2008. e-Pub 7/2008. PMCID: PMC2556461.
27. Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, Shah B, Chang SH, Schluns KS, Watowich SS, Feng XH, Jetten AM, Dong C. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 29(1):44-56, 7/2008. e-Pub 6/2008. PMCID: PMC2630532.
28. Yamazaki T, Yang XO, Chung Y, Fukunaga A, Nurieva R, Pappu B, Martin-Orozco N, Kang HS, Ma L, Panopoulos AD, Craig S, Watowich SS, Jetten AM, Tian Q, Dong C. CCR6 regulates the migration of inflammatory and regulatory T cells. J Immunol 181(12):8391-401, 12/2008. PMCID: PMC2752441.
29. Nurieva R, Yang XO, Chung Y, Dong C. Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts. J Immunol 182(5):2565-8, 3/2009. PMCID: PMC2755098.
30. Chung Y, Chang SH, Martinez GJ, Yang XO, Nurieva R, Kang HS, Ma L, Watowich SS, Jetten AM, Tian Q, Dong C. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30(4):576-87, 4/2009. e-Pub 4/2009. PMCID: PMC2705871.
31. Liu X, Alexiou M, Martin-Orozco N, Chung Y, Nurieva RI, Ma L, Tian Q, Kollias G, Lu S, Graf D, Dong C. Cutting edge: A critical role of B and T lymphocyte attenuator in peripheral T cell tolerance induction. J Immunol 182(8):4516-20, 4/2009. PMCID: PMC2767106.
32. Wang Y, Li D, Nurieva R, Yang J, Sen M, Carreño R, Lu S, McIntyre BW, Molldrem JJ, Legge GB, Ma Q. LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells. J Biol Chem 284(19):12645-53, 5/2009. e-Pub 3/2009. PMCID: PMC2675993.
33. Nurieva RI, Liu X, Dong C. Yin-Yang of costimulation: crucial controls of immune tolerance and function. Immunol Rev 229(1):88-100, 5/2009. PMCID: PMC2875245.
34. Nurieva RI, Chung Y, Martinez GJ, Yang XO, Tanaka S, Matskevitch TD, Wang YH, Dong C. Bcl6 mediates the development of T follicular helper cells. Science 325(5943):1001-5, 8/2009. e-Pub 7/2009. PMCID: PMC2857334.
35. Zhang Y, Reynolds JM, Chang SH, Martin-Orozco N, Chung Y, Nurieva RI, Dong C. MKP-1 is necessary for T cell activation and function. J Biol Chem 284(45):30815-24, 11/2009. e-Pub 9/2009. PMCID: PMC2781480.
36. Yang XO, Angkasekwinai P, Zhu J, Peng J, Liu Z, Nurieva R, Liu X, Chung Y, Chang SH, Sun B, Dong C. Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment. Nat Immunol 10(12):1260-6, 12/2009. e-Pub 11/2009. PMCID: PMC2784129.
37. Nurieva RI, Zheng S, Jin W, Chung Y, Zhang Y, Martinez GJ, Reynolds JM, Wang SL, Lin X, Sun SC, Lozano G, Dong C. The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. Immunity 32(5):670-80, 5/2010. e-Pub 5/2010. PMCID: PMC2915546.
38. Reynolds JM, Pappu BP, Peng J, Martinez GJ, Zhang Y, Chung Y, Ma L, Yang XO, Nurieva RI, Tian Q, Dong C. Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease. Immunity 32(5):692-702, 5/2010. e-Pub 4/2010. PMCID: PMC2878917.
39. Nurieva RI, Chung Y. Understanding the development and function of T follicular helper cells. Cell Mol Immunol 7(3):190-7, 5/2010. e-Pub 4/2010. PMCID: PMC4002918.
40. Nurieva RI, Liu X, Dong C. Molecular mechanisms of T-cell tolerance. Immunol Rev 241(1):133-44, 5/2011. PMCID: PMC5131796.
41. Chung Y, Tanaka S, Chu F, Nurieva RI, Martinez GJ, Rawal S, Wang YH, Lim H, Reynolds JM, Zhou XH, Fan HM, Liu ZM, Neelapu SS, Dong C. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat Med 17(8):983-8, 7/2011. e-Pub 7/2011. PMCID: PMC3151340.
42. Xu T, Wang X, Zhong B, Nurieva RI, Ding S, Dong C. Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein. J Biol Chem 286(26):22707-10, 7/2011. e-Pub 5/2011. PMCID: PMC3123037.
43. Wang X, Zhang Y, Yang XO, Nurieva RI, Chang SH, Ojeda SS, Kang HS, Schluns KS, Gui J, Jetten AM, Dong C. Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2. Immunity 36(1):23-31, 1/2012. e-Pub 1/2012. PMCID: PMC3270375.
44. Nurieva RI, Podd A, Chen Y, Alekseev AM, Yu M, Qi X, Huang H, Wen R, Wang J, Li HS, Watowich SS, Qi H, Dong C, Wang D. STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. J Biol Chem 287(14):11234-9, 3/2012. e-Pub 2/2012. PMCID: PMC3322890.
45. Bollig N, Brüstle A, Kellner K, Ackermann W, Abass E, Raifer H, Camara B, Brendel C, Giel G, Bothur E, Huber M, Paul C, Elli A, Kroczek RA, Nurieva R, Dong C, Jacob R, Mak TW, Lohoff M. Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation. Proc Natl Acad Sci U S A 109(22):8664-9, 5/2012. e-Pub 5/2012. PMCID: PMC3365194.
46. Ma Q, Li D, Nurieva R, Patenia R, Bassett R, Cao W, Alekseev AM, He H, Molldrem JJ, Kroll MH, Champlin RE, Sale GE, Afshar-Kharghan V. Reduced graft-versus-host disease in C3-deficient mice is associated with decreased donor Th1/Th17 differentiation. Biol Blood Marrow Transplant 18(8):1174-81, 8/2012. e-Pub 6/2012. PMCID: PMC3437318.
47. Liu X, Yan X, Zhong B, Nurieva RI, Wang A, Wang X, Martin-Orozco N, Wang Y, Chang SH, Esplugues E, Flavell RA, Tian Q, Dong C. Bcl6 expression specifies the T follicular helper cell program in vivo. J Exp Med 209(10):1841-52, S1-24, 9/2012. e-Pub 9/2012. PMCID: PMC3457730.
48. Glasmacher E, Agrawal S, Chang AB, Murphy TL, Zeng W, Vander Lugt B, Khan AA, Ciofani M, Spooner CJ, Rutz S, Hackney J, Nurieva R, Escalante CR, Ouyang W, Littman DR, Murphy KM, Singh H. A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes. Science 338(6109):975-80, 11/2012. e-Pub 9/2012. PMCID: PMC5789805.
49. Liu X, Nurieva RI, Dong C. Transcriptional regulation of follicular T-helper (Tfh) cells. Immunol Rev 252(1):139-45, 3/2013. PMCID: PMC3579502.
50. Blonska M, Joo D, Nurieva RI, Zhao X, Chiao P, Sun SC, Dong C, Lin X. Activation of the transcription factor c-Maf in T cells is dependent on the CARMA1-IKKβ signaling cascade. Sci Signal 6(306):ra110, 12/2013. e-Pub 12/2013. PMCID: PMC5762115.
51. Liu X, Chen X, Zhong B, Wang A, Wang X, Chu F, Nurieva RI, Yan X, Chen P, van der Flier LG, Nakatsukasa H, Neelapu SS, Chen W, Clevers H, Tian Q, Qi H, Wei L, Dong C. Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development. Nature 507(7493):513-8, 3/2014. e-Pub 1/2014. PMCID: PMC4012617.
52. Qin H, Lerman B, Sakamaki I, Wei G, Cha SC, Rao SS, Qian J, Hailemichael Y, Nurieva R, Dwyer KC, Roth J, Yi Q, Overwijk WW, Kwak LW. Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice. Nat Med 20(6):676-81, 6/2014. e-Pub 5/2014. PMCID: PMC4048321.
53. Tanaka S, Tanaka K, Magnusson F, Chung Y, Martinez GJ, Wang YH, Nurieva RI, Kurosaki T, Dong C. CCAAT/enhancer-binding protein α negatively regulates IFN-γ expression in T cells. J Immunol 193(12):6152-60, 12/2014. e-Pub 11/2014. PMCID: PMC4385522.
54. Sahoo A, Alekseev A, Tanaka K, Obertas L, Lerman B, Haymaker C, Clise-Dwyer K, McMurray JS, Nurieva R. Batf is important for IL-4 expression in T follicular helper cells. Nat Commun 6:7997, 8/2015. e-Pub 8/2015. PMCID: PMC4557271.
55. Cao AT, Yao S, Gong B, Nurieva RI, Elson CO, Cong Y. Interleukin (IL)-21 promotes intestinal IgA response to microbiota. Mucosal Immunol 8(5):1072-82, 9/2015. e-Pub 1/2015. PMCID: PMC4501922.
56. Mandal PK, Morlacchi P, Knight JM, Link TM, Lee GR, Nurieva R, Singh D, Dhanik A, Kavraki L, Corry DB, Ladbury JE, McMurray JS. Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity. J Med Chem 58(22):8970-84, 11/2015. e-Pub 11/2015. PMCID: PMC5109833.
57. Venkatasubramanian S, Cheekatla S, Paidipally P, Tripathi D, Welch E, Tvinnereim AR, Nurieva R, Vankayalapati R. IL-21-dependent expansion of memory-like NK cells enhances protective immune responses against Mycobacterium tuberculosis. Mucosal Immunol 10(4):1031-1042, 7/2017. e-Pub 12/2016. PMCID: PMC5462891.
58. Haymaker C, Yang Y, Wang J, Zou Q, Sahoo A, Alekseev A, Singh D, Ritthipichai K, Hailemichael Y, Hoang ON, Qin H, Schluns KS, Wang T, Overwijk WW, Sun SC, Bernatchez C, Kwak LW, Neelapu SS, Nurieva R. Absence of Grail promotes CD8+ T cell anti-tumour activity. Nat Commun 8(1):239, 8/2017. e-Pub 8/2017. PMCID: PMC5552797.
59. Na H, Lim H, Choi G, Kim BK, Kim SH, Chang YS, Nurieva R, Dong C, Chang SH, Chung Y. Concomitant suppression of TH2 and TH17 cell responses in allergic asthma by targeting retinoic acid receptor-related orphan receptor γt. J Allergy Clin Immunol. e-Pub 9/2017. PMCID: PMC5862762.
60. Kim BS, Lu H, Ichiyama K, Chen X, Zhang YB, Mistry NA, Tanaka K, Lee YH, Nurieva R, Zhang L, Yang X, Chung Y, Jin W, Chang SH, Dong C. Generation of RORγt+ Antigen-Specific T Regulatory 17 Cells from Foxp3+ Precursors in Autoimmunity. Cell Rep 21(1):195-207, 10/2017. PMCID: PMC5716359.
61. Cheekatla SS, Tripathi D, Venkatasubramanian S, Paidipally P, Welch E, Tvinnereim AR, Nurieva R, Vankayalapati R. IL-21 Receptor Signaling Is Essential for Optimal CD4+ T Cell Function and Control of Mycobacterium tuberculosis Infection in Mice. J Immunol 199(8):2815-2822, 10/2017. e-Pub 8/2017. PMCID: PMC5636679.
62. Ritthipichai K, Haymaker CL, Martinez M, Aschenbrenner A, Yi X, Zhang M, Kale C, Vence LM, Roszik J, Hailemichael Y, Overwijk WW, Varadarajan N, Nurieva R, Radvanyi LG, Hwu P, Bernatchez C. Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter. Clin Cancer Res 23(20):6151-6164, 10/2017. e-Pub 7/2017. PMCID: PMC5748156.
63. Taghavie-Moghadam PL, Waseem TC, Hattler J, Glenn LM, Dobrian AD, Kaplan MH, Yang Y, Nurieva R, Nadler JL, Galkina EV. STAT4 Regulates the CD8+ Regulatory T Cell/T Follicular Helper Cell Axis and Promotes Atherogenesis in Insulin-Resistant Ldlr-/- Mice. J Immunol 199(10):3453-3465, 11/2017. e-Pub 10/2017. PMCID: PMC5675741.
64. Khosravi N, Caetano MS, Cumpian AM, Unver N, De la Garza Ramos C, Noble O, Daliri S, Hernandez BJ, Gutierrez BA, Evans SE, Hanash S, Alekseev AM, Yang Y, Chang SH, Nurieva R, Kadara H, Chen J, Ostrin EJ, Moghaddam SJ. IL22 Promotes Kras Mutant Lung Cancer by Induction of a Pro-Tumor Immune Response and Protection of Stemness Properties. Cancer Immunol Res. e-Pub 5/2018. PMID: 29764837.
65. Qin L, Waseem TC, Sahoo A, Bieerkehazhi S, Zhou H, Galkina EV, Nurieva R. Insights Into the Molecular Mechanisms of T Follicular Helper-Mediated Immunity and Pathology. Front Immunol 9:1884, 2018. e-Pub 8/2018. PMCID: PMC6104131.
1. Nurieva R, Wang J, Sahoo A. T-cell tolerance in cancer. Immunotherapy 5(5):513-531, 5/2013. PMCID: PMC5103631.
2. Sahoo A, Wali S, Nurieva R. T helper 2 and T follicular helper cells: Regulation and function of interleukin-4. Cytokine Growth Factor Rev 30:29-37, 8/2016. e-Pub 3/2016. PMCID: PMC5110032.
3. Wali S, Sahoo A, Puri S, Alekseev A, Nurieva R. Insights into the development and regulation of T follicular helper cells. Cytokine 87:9-19, 11/2016. e-Pub 6/2016. PMCID: PMC5108526.
4. Haymaker CL, Hailemichael Y, Yang Y, Nurieva R. In Vivo Assay for Detection of Antigen-specific T-cell Cytolytic Function Using a Vaccination Model. J Vis Exp(129), 11/2017. e-Pub 11/2017. PMCID: PMC5755481.
1. Nurieva RI, Dong C. Keeping autoimmunity in check: how to control a Th17 cell controller. Immunity 29(6):841-3, 12/2008. PMID: 19100696.
2. Nurieva RI, Dong C. (IL-)12 and 21: a new kind of help in the follicles. Immunol Cell Biol 87(8):577-8, Nov-Dec, 11/2009. PMID: 19907426.
1. Dong C, Nurieva RI, Martin-Orozco N. Immune regulation and immunotherapy of autoimmune disease. In: Costimulation Regulation of Immune Tolerance and Autoimmunity. Ed(s) J Zhang. Springer US, Life Sciences, 121-138, 2007. PMID: 978-0-387-36002-7.
2. Dong C, Chang S, Yang X, Nurieva R. Inflammatory T cells: regulation, function and pathological roles in disease. In: Effector CD4 T Cell Subsets in Health and Disease. Ed(s) S Na and C Iyer. Research Signpost, 65-84, 2007. PMID: 978-81-7895-310-6.
3. Martinez GJ, Nurieva RI, Yang XO, Dong C. Regulation and function of proinflammatory TH17 cells. In: Ann N Y Acad Sci. 1143. Ed(s) NR Rose. Wiley: New York, 188-211, 11/2008. PMID: 19076351.
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