Prof. Yingliang Wu
Tel : 86 - 27 - 6875-2831
Fax : 86 - 27 - 6875-6746
College of Life Sciences, Wuhan University
Research Interests:
(1) Protein-protein recognition mechanism
(2) Biomolecular information and engineering
Publications
1) Ying Wu, Yu Xiong, Sheng Wang, Hong Yi, Hui Li, Na Pan, Frank T Horrigan Yingliang Wu*, Jiuping Ding*. Inter-subunit coupling in the Pore of BK channels, J. Biol. Chem. 2009,284(35):23353-23363
2) Shijin Yin, Ling Jiang, Hong Yi, Song Han, Daiwen Yang, Maili Liu, Hui Liu, Zhijian Cao, Yingliang Wu*, Wenxin Li*. Different residues in channel turret determining the selectivity of ADWX-1 inhibitor peptide between Kv1.1 and Kv1.3 channels. Journal of Proteome Research, 2008, 7(11): 4890-4897
3) Geliang Gan, Hong Yi, Maorong Chen, Liang Sun, Wenxin Li, Yingliang Wu* and Jiuping Ding*. Structural basis for toxin-resistance of beta4 associated calcium-activated potassium (BK) channels. Journal of Biological Chemistry, 2008, 283: 24177-24184
4) Song Han, Hong Yi, Shi-Jin Yin, Zong-Yun Chen, Hui Liu, Zhi-Jian Cao, Ying-Liang Wu*, and Wen-Xin Li*. Structural Basis of a Potent Peptide Inhibitor Designed for Kv1.3 Channel, a Therapeutic Target of Autoimmune Disease. Journal of Biological Chemistry, 2008, 283: 19058-19065
5) Yi H, Qiu S, Cao ZJ, Wu YL*, Li WX*. Molecular basis of inhibitory peptide maurotoxin recognizing Kv1.2 channel explored by ZDOCK and molecular dynamic simulations. PROTEINS: Structure, Function, and Bioinformatics, 2008, 70:744-54
6) Jin L*, Wu Y*.Molecular Mechanism of the Sea Anemone Toxin ShK Recognizing the Kv1.3 Channel Explored by Docking and Molecular Dynamic Simulations. Journal of Chemical Information and Modeling, 2007, 47: 1967-1972
7) Hong Yi, Zhijian Cao, Shijin Yin, Chao Dai, Yingliang Wu*, Wenxin Li*. Interaction Simulation of hERG K+ Channel with its specific Bekm-1 peptide: Insights into the Selectivity of Molecular Recognition. Journal of Proteome Research, 2007, 6: 611-620
8) Yingliang Wu, Hong Yi, Zhijian Cao, Wenxin Li. Conformation of Trimeric Envelope Glycoproteins: The CD4-dependent Membrane Fusion Mechanism of HIV-1. Journal of Biomolecular Structure & Dynamics, 2007, 25: 1-9
9) Mouhat S, Homerick D, Visan V, Wulff H, Wu Y, Grissmer S, Darbon H, Waard M, Sabatier JM. Pharmacological profiling of Orthochirus scrobiculosus toxin 1 analogs with a trimmed N-terminal domain. Molecular Pharmacology, 2006, 69: 354-362
10) Yingliang Wu, Zhijian Cao, Hong Yi, Dahe Jiang, Xin Mao, Hui Liu and Wenxin Li. Simulation of the interaction between ScyTx and small conductance calcium-activated potassium channel by docking and MM-PBSA. Biophysical Journal, 2004, 87(1): 105-112
11) Yingliang Wu, Bin Hu, Zucheng Jiang. A low temperature vaporization for ICP-AES determination of palladium in geological samples using sample introduction of gaseous palladium oxinate. Journal of Analytical Atomic Spectrometry, 2002, 17(1): 121-124
12) Yingliang Wu, Bin Hu, Tianyou Peng, Zhenhuan Liao, Zucheng Jiang. Electrothermal volatilization of aluminum as 1-phenyl-3-methyl-4-benzoylpyrazolone[5] chelate for gaseous sample introduction in ICP-AES. Talanta, 2001, 55(4): 841-845
13) Wu, YL; Hu, B; Peng, TY; Jiang, ZC. Low-temperature volatilization of Be acetylacetonate for sample introduction in ETV-ICP-AES. Analytical Chimica Acta, 2001, 439 (1): 153-158